Seronegative rheumatoid arthritis is nothing but a type of arthritis where rheumatoid factor (R F) is not found in the blood. The presence of this disease could be well determined by the doctors by having a blood test for rheumatoid factor. Some patient shows the negative of rheumatoid factor in spite of having all the arthritic symptoms. There are various blood test done to determine the rheumatoid factor in a patient and they are, the erythrocyte sedimentation rate (E S R), complete blood count (C B C), C-reactive protein (CRP), antinuclear antibodies, and some sort of X-rays. Diagnosing rheumatoid arthritis (R A) is not so easy task as it includes some series of blood test. This seronegative rheumatoid arthritis is found in men rather than women.
Symptoms of seronegative rheumatoid arthritis
Common symptoms of seronegative rheumatoid arthritis and seropositive R A, goes parallel, because they come with same type of symptoms. The common symptoms may be inflammation of tender joints, pain, stiffness of joints especially in the morning for at least one hour, flu like symptoms, pain in muscles and limitation in some movement. Some other symptoms that accompany a patient are fatigue, weakness, fever, and stiffness to the body. Generally pain and limitation of movement is found in the synovial joints of ankles, wrist, neck, and shoulder. Doctors find some kind of difficulty in monitoring this disease because of the absence of rheumatoid facto in the blood, which somehow shows the intense of the disease or how far it has developed. From rheumatoid factor it becomes impossible for the doctors to estimates the severity of this seronegative rheumatoid arthritis.
Treatment of seronegative rheumatoid arthritis
The observing and documenting the occurrence and reoccurrence of the flares is the basic treatment or remedy suggested by the doctors to the patients. By maintaining the calendar of flares, a doctor can estimate the condition that takes place between the periods of remission. Depending upon the frequency and severity of the flares, a doctor determines the seriousness of the disease as because a patient does not show any signs of rheumatoid factor in their blood test. The treatment of seronegative rheumatoid arthritis is as same as that of seropositive rheumatoid arthritis because on both the cases doctors focuses on relief from swelling, pain, and minimizing the destruction of joints, cells, tendons, and tissues. The drugs prescribed for the treatment of this disease are non steroidal anti inflammatory drugs (N S A I D), disease modifying anti rheumatic drugs (D M A R D), biological response modifiers, and corticosteroids injection, which are directly injected to the affected area of the joints.
According to some research it has been found that patients suffering from seronegative rheumatoid arthritis are comparatively less prone to have joint destruction and erosion than that in seropositive R A. Not only that they are also less prone to the formation of nodules under their skin. Though the majority of symptoms of seronegative rheumatoid arthritis are same as that of seropositive, but the intensity is very less as compared to each other.