Sulfasalazine whose brand name is Azulfidine or sulfazine, and was known to have developed 70 years ago in order to treat rheumatoid arthritis as at that time it was believed by many scientists that cause of rheumatoid arthritis was some bacterial infections. Sulfasalazine rheumatoid arthritis is known for reducing the inflammation of the joints and even slows the progression of the disease from getting worse. Not only has that it also helped in treating inflammatory bowel disease. Sulfasalazine is a type of sulfa drug and is made with the combination of sulfapyridine and salicylate forming an azo bond. In the inception of this disease sulfasalazine is used to treat the milder cases of rheumatoid arthritis. It is sometimes used in the combination of other drugs like disease non steroidal anti inflammatory drugs (N S A I D s) and disease modifying anti rheumatic drugs (D M A R D s) for treating more severe cases of rheumatoid arthritis. According to some studies it has been revealed that sulfasalazine is very useful in monitoring the symptoms and decreasing the progression of rheumatoid arthritis. The result may be seen within a month but in general it takes few months to get effective.
Side effects of sulfasalazine rheumatoid arthritis
Sulfasalazine is a low dosage drug which a patient can easily tolerate but has been seen with some side effects in some rare cases. It can cause rash in the skin, some sort of discomfort in the abdominal area, nausea, low blood counts, and some allergic reaction.
Dosage of sulfasalazine rheumatoid arthritis
Sulfasalazine is found in a 500 mg tablet form and is consumed with food at a time in order to prevent the problem of the abdominal area. In inception a low dosage of sulfasalazine rheumatoid arthritis that is 500 mg is provided to the patient in order to have a low side effect. As the course increases the dosage also increases from one tablet to two tablets per day and so on. The dosage may be as high as 3000 mg per day. In order to avoid the side effect of stomach upset an Enteric coated is done to the patient.
Sulfasalazine regarding pregnant woman
Sulfasalazine does not affect the fertility of a woman but it is known to affect the fertility of a man by reducing the sperm mobility. A man wishing to conceive a child with his partner is advised to discontinue the consumption of Sulfasalazine minimum 3 months before getting the preparation for it. For pregnant woman who wants disease modifying therapy can use Sulfasalazine as one of the prescribed D M A R D s.
Some facts of Sulfasalazine rheumatoid arthritis
A combined therapy of methotrexate, sulfasalazine, and hydroxychloroquine is found more effective than the combination of sulfasalazine and hydroxychloroquine for the opatient of rheumatoid arthritis. Thus Sulfasalazine rheumatoid arthritis is very profitable for the patients of this disease as it has very meager side effects and can be consumed by both the sections of the society with effective results.